ONGOING R&D PROJECTS

AronPharma is currently developing three different projects co-financed by the European Union.
Original products rich in polyphenol compounds obtained from berries and other polyphenol-rich plants
will be created within the framework of these projects.

METARON

Development of natural based products, extracts rich in polyphenolic compounds supporting the treatment of diabetes.

Goals of the project: The main goal of the project realization is the introduction to the market of the brand new products, based on natural extracts, rich in polyphenolic compounds, like chokeberry, evening primrose and other polyphenol-rich plants. The mechanism of activity is the support of the metformin treatment, as well as the cytoprotective activity, reducing the intolerance to the used drugs.

An additional aspect would be the treatment support of the prediabetes, which is a serious health condition, where blood sugar level is higher than normal, but not high enough to be diagnosed as type 2 diabetes. The prediabetes health condition increases the risk of the metabolic syndrome: type 2 diabetes, heart diseases and stroke.

Planned effects: as the result of the project we will obtain a brand new, not existing before on the market blend of different extracts with a high polyphenol content. We will obtain the appropriate formulation of the product with a higher bioavailability of the polyphenolic compounds and the formulation with an increased activity in the intestines.

Value of the project: 3 948 188,70 PLN

Value of the co-financing: 2 960 982,92 PLN

Time of realization: 2019 – 2023

COVIDARON

Development of an effective therapy to strengthen the immune system, regenerate the organism and prevent the coronavirus  SARS-CoV-2 infection.

The SARS-CoV-2 virus, the pathogen from the coronaviruses family is responsible for causing acute infectious respiratory disease. The immune response is essential to defend, control and eliminate CoV infections. The main goal is to launch a new effective therapy to strengthen the immune system and thereby coronavirus SARS-CoV-2 prevention in the era of pandemic COVID-19.

In recent years, the advances in liposome research have acknowledged them as pharmaceutical carrier. Liposomes have not only antibacterial, but also antiviral applications. The aim of this project is the introduction to the market of innovative liposomes with both antiviral and anti-inflammatory properties. Our purpose is also vitamins, minerals, active substances, aromatic compounds and standardized polyphenol and anthocyanins-rich extracts encapsulation in liposomes, as well as an improvement of their bioavailability and stability. There are losses in excipients with standard diet supplement production. Liposomal supplement guarantees its load delivery. This will enhance the immune system and therefore it will lead to prevention SARS-CoV-2 virus spread.

Value of the project:  6 050 170,00 PLN

Value of the co-financing: 4 336 063,00 PLN

Time of realization: 2020 – 2023

ONCOARON

Development of innovative products rich in polyphenolic compounds obtained from berries for use in the prophylaxis and prevention of side effects of oncological therapy, chemotherapy and radiation therapy.

The goal of the project is the introduction to the market of the brand new products, based on berries extracts, especially chokeberry extract, which will demonstrate cytoprotective properties and will reduce the side effects of chemo- and radio- therapy without causing any undesirable effects. Thanks to the realization of this project we will develop and obtain a product being a completely new, not existing before blend of different botanical extracts with very high anthocyanins (>20%) and polyphenols (>45%) content.

Value of the project:   4 907 693,35 PLN

Value of the co-financing: 3 214 109,89 PLN

Time of realization: 2020 – 2023

ADDITIONAL CLINICAL TRIALS

Formulation development

Comparison of bioavailability
of vitamin C and D3 in traditional
and liposomal form.

Vision protection

Study of effectof a combination
of polyphenol-rich extracts
on the protection of retinal
cells against blue light induced
eye diseases.

Gastric function support

Study of effect of a combination
of polyphenol-rich extracts,
probiotics and hydrolyzed fiber on
the quality of life of patients with
irritable bowel syndrome (IBS).

Cardio protection

Comparison of the effects
of standardized chokeberry
extract with different
formulations on the levels of
selected markers associated
with cardiovascular disease.

Nutraceuticals and Food Supplements Manufacturer

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AronPharma 2022. All rights reserved.

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